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Novel Applications Beyond Oncology:
CNS Discovery
Autoimmune Diseases
Cerebral Ischemia
Cardiovascular Diseases
Next Generation Tumor Targets:
Novel Multiplex PI3K Inhibitors
Mitotic Spindle Kinase Inhibitors
Novel Peptide Modulator
Current (and Next) Challenges in Industry:
Specificity
Efficacy
Resistence
Pharmacokinetics
Next Generation Design Strategies:
Novel High-Throughput Binding Assays
Structure-Based Designs
Lead Optimization
Screening for Allosteric Inhibitor
With the kinase inhibitor field developing rapidly, novel applications beyond oncology are in hot pursuit. In addition to novel results in oncology, this conference will present developments in areas such as CNS, pain, anti-inflammatories, autoimmune diseases, cardiotoxicity, diabetes and more. In addition, prioritizing targets has become extremely important and optimized screening technologies are needed to keep up with the current pace. Key issues such as developing lead compounds, integrating chemistry and biology, using promising techniques such as fragment and structure-based design as well as optimizing PK and PD and how to analyze the flood of data available will be addressed.
Take advantage of the opportunity to learn and discuss state-of-the-art projects in novel and promising areas in the field of kinase inhibitors.