September 24, 2014
11 am to 12 pm EDT

Sponsored by

Webinar Description:

Knowledge of the involvement of the innate and adaptive immune systems is relevant to the vast majority of disease models. Consequently the ability to integrate advanced immunological methods into pre-clinical models of disease markedly enhances their predictive value in the drug development process. Thus the application of flow cytometry, fluorescence- and magnetic-activated cell sorting, and adoptive transfers of immune cells have resulted in creating robust platforms from which potential interventions for immunologically-based diseases can be effectively and accurately evaluated. This webinar discusses the general application of immunological techniques to enhance the in-life and end-point analysis of existing disease models, as well as highlighting the use of specific sorted immune cells in two adoptive transfer-based models of graft versus host disease and colitis.

Learning Objectives:

• Understanding the Application of Flow Cytometry and Cell Sorting
• Advantages of Utilizing Immunological Techniques in Disease Models
• Introduction to GVHD and Adoptive Transfer Colitis Models

Speakers:

Dominic R. Beal, Ph.D.

Associate Scientist
Biomodels, LLC

Dr. Beal joined Biomodels in 2013 as an associate scientist after completing his doctoral studies at Boston University School of Medicine, where he studied the role of macrophage phenotypes in the immuno-pathology of asthma. He previously lived in England where he received his MSc in the immunology of infectious disease from the London School of Hygiene & Tropical Medicine, studying the effects of malaria-schistosomiasis co-infections on dendritic cell function, and his MA from Trinity Hall at the University of Cambridge. Dr. Beal's main areas of interest are immune cell interactions and the mechanisms underlying the generation and manipulation of immune responses by pathogens and disease states.

Cost: No cost!