Short Courses

Tuesday, June 14
12:00 – 3:00 pm

SC4: Modern Lead Generation Strategies - Part 1 - Detailed Agenda

Lead Generation is where chemical project assets are first created, and as such it is the area of Medicinal Chemistry that most strongly influences timelines and attrition rates. This discipline has undergone significant paradigm changes within recent years as new hit generation techniques have emerged and novel lead characterization methods have been invented. This two part short course will give a comprehensive and up to date review of the field along with many practical examples and is intended for a broader audience ranging from beginner to advanced level.

Part 1 will introduce lead generation and the different hit generation methods available today.

Download Podcast with Joerg Holenz

Chairperson:

Joerg Holenz, Ph.D., Director, Discovery and Preclinical Sciences; Project Leader, Neuroscience iMed, AstraZeneca Neuroscience

Instructors:

Tim Cernak, Ph.D., Associate Principal Scientist, Discovery Chemistry, Automation & Capabilities Enhancement, Merck Boston

Rajiah Aldrin Denny, Ph.D., Senior Principal Scientist, Cheminformatics and Computational Chemist, Pfizer, Inc.

Ivan V. Efremov, Ph.D., Senior Principal Scientist, Worldwide Medicinal Chemistry, Pfizer, Inc.

Matthew Clark, Ph.D., Senior Vice President, Research, X-Chem

Tuesday, June 14
3:30 – 6:30 pm

SC7: Modern Lead Generation Strategies - Part 2 - Detailed Agenda

Lead Generation is where chemical project assets are first created, and as such it is the area of Medicinal Chemistry that most strongly influences timelines and attrition rates. This discipline has undergone significant paradigm changes within recent years as new hit generation techniques have emerged and novel lead characterization methods have been invented. This two-part short course will give a comprehensive and up-to-date review of the field along with many practical examples and is intended for a broader audience ranging from beginner to advanced level.

Part 2 will center on how to convert these hits to leads and the most recent trends in lead generation.

Download Podcast with Joerg Holenz

Chairperson:

Joerg Holenz, Ph.D., Director, Discovery and Preclinical Sciences; Project Leader, Neuroscience iMed, AstraZeneca Neuroscience

Instructors:

Dean Brown, Ph.D., Director, Discovery and Preclinical Sciences, AstraZeneca

John Mathias, Ph.D., Senior Director, Cystic Fibrosis Program Leader, Pfizer, Inc.

Erin F. DiMauro, Ph.D., Principal Scientist, Medicinal Chemistry, Amgen, Inc.

Ivan Cornella-Taracido, Senior Principal Scientist, Discovery Chemistry, Merck

Jeremy Scott, Ph.D., Senior Director, Chemistry, Vertex